ATP-INDUCED K- A UNIQUE PURINOCEPTOR( CURRENT OSCILLATION IN MEGAKARYOCYTES )

Authors
AKAIKE N UNEYAMA H
Citation
N. Akaike et H. Uneyama, ATP-INDUCED K- A UNIQUE PURINOCEPTOR( CURRENT OSCILLATION IN MEGAKARYOCYTES ), News in physiological sciences, 9, 1994, pp. 49-53
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
9
Year of publication
1994
Pages
49 - 53
Database
ISI
SICI code
0886-1714(1994)9:<49:AKAUPC>2.0.ZU;2-L
Abstract
Megakaryocytes respond to externally applied ATP and ADP, showing a pe riodic K+ current that reflects oscillation in cytoplasmic calcium con centration (Ca2+(i)). The agonist selectivity of the purinoceptor on the megakaryocyte is unique. In addition, the intracellular mechanism of Ca2+(i) oscillation was investigated, and a model is proposed.