MOLECULAR MECHANISMS OF MECHANORECEPTOR ADAPTATION

Authors
HAMILL OP MCBRIDE DW
Citation
Op. Hamill et Dw. Mcbride, MOLECULAR MECHANISMS OF MECHANORECEPTOR ADAPTATION, News in physiological sciences, 9, 1994, pp. 53-59
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
9
Year of publication
1994
Pages
53 - 59
Database
ISI
SICI code
0886-1714(1994)9:<53:MMOMA>2.0.ZU;2-P
Abstract
Mechanoreceptor adaptation to maintained stimulation serves to maximiz e dynamic sensitivity over a broad stimulus domain. Mechanosensitive c hannel currents in hair cells and oocytes show similar voltage-depende nt adaptation. However, in the hair cell, adaptation appears dependent on Ca2+ influx, whereas in the oocyte, it is intrinsically voltage se nsitive.