NITRIC-OXIDE SYNTHASE - FROM MOLECULAR-BIOLOGY TO CEREBROVASCULAR PHYSIOLOGY

Authors
KATUSIC ZS COSENTINO F
Citation
Zs. Katusic et F. Cosentino, NITRIC-OXIDE SYNTHASE - FROM MOLECULAR-BIOLOGY TO CEREBROVASCULAR PHYSIOLOGY, News in physiological sciences, 9, 1994, pp. 64-67
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
9
Year of publication
1994
Pages
64 - 67
Database
ISI
SICI code
0886-1714(1994)9:<64:NS-FMT>2.0.ZU;2-S
Abstract
Three distinct nitric oxide synthase genes are expressed in the cerebr al arterial wall. Constitutive isoforms are localized in endothelium a nd perivascular nerves, whereas only inducible enzyme is present in sm ooth muscle cells, demonstrating the complex role of nitric oxide in r egulation of cerebral arterial tone.