MACROPHAGES IN THE BRAIN - FRIENDS OR ENEMIES

Authors
PIANI D CONSTAM DB FREI K FONTANA A
Citation
D. Piani et al., MACROPHAGES IN THE BRAIN - FRIENDS OR ENEMIES, News in physiological sciences, 9, 1994, pp. 80-84
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
9
Year of publication
1994
Pages
80 - 84
Database
ISI
SICI code
0886-1714(1994)9:<80:MITB-F>2.0.ZU;2-U
Abstract
Cells of the macrophage lineage are ubiquitously distributed in the bo dy, including the central nervous system. They represent an essential host defense system to protect from infections. However, recent eviden ce indicates that brain macrophages may also be responsible for tissue destruction, including loss of neurons and demyelination.