AN ANTILEISHMANIAL CHALCONE FROM CHINESE LICORICE ROOTS

Authors
CHRISTENSEN SB MING C ANDERSEN L HJORNE U OLSEN CE CORNETT C THEANDER TG KHARAZMI A
Citation
Sb. Christensen et al., AN ANTILEISHMANIAL CHALCONE FROM CHINESE LICORICE ROOTS, Planta medica, 60(2), 1994, pp. 121-123
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
60
Issue
2
Year of publication
1994
Pages
121 - 123
Database
ISI
SICI code
0032-0943(1994)60:2<121:AACFCL>2.0.ZU;2-5
Abstract
A bioassay guided fractionation of an extract of Chinese licorice root s led to the isolation of droxy-3-(3-methyl-2-butenylphenyl-2-propen- 1-one, which in vitro showed potent antileishmanial activity. In addit ion, the novel chalcone tenyl-8-hydroxy-2H-benzopyran-6-yl)-2-propen-1 -one was isolated from the roots. The latter compound only showed anti leishmanial activity at high concentrations.