CALCULATION OF NEUTRON ENERGY DEPOSITION IN NANOMETRIC SITES

Simulations of charged particle tracks in water vapour were used to bu ild a parametric model enabling the calculation of ionisation distribu tions in spherical targets, including the influence of straggling and delta rays. The model has been applied to assess neutron energy deposi tion in nanometric sites in tissue. Emission and slowing down spectra of charged particles from neutron interactions and of photo-induced el ectrons were combined with the model. All kinds of ionisation events w ere taken into account, although in such small sites crossers and touc hers definitely predominate. The approach has been coupled with macros copic radiation transport calculations, thus allowing for biophysical modelling of realistic radiobiological situations.