DEVELOPMENT OF PCR-SSOP FOR THE IDENTIFICATION OF HLA-A-ASTERISK-02 SUBTYPES AND DETERMINATION OF HLA-A-ASTERISK-02 FREQUENCIES WITHIN DIFFERENT ETHNIC POPULATIONS

Authors
WILLIAMS F MIDDLETON D SAVAGE D GORODEZKY C WILSON DWL FITZGERALD JM URBANIAK SJ
Citation
F. Williams et al., DEVELOPMENT OF PCR-SSOP FOR THE IDENTIFICATION OF HLA-A-ASTERISK-02 SUBTYPES AND DETERMINATION OF HLA-A-ASTERISK-02 FREQUENCIES WITHIN DIFFERENT ETHNIC POPULATIONS, Tissue antigens, 49(2), 1997, pp. 129-133
Citations number
17
Categorie Soggetti
Immunology,"Cell Biology
Journal title
Tissue antigens → ACNP
ISSN journal
00012815
Volume
49
Issue
2
Year of publication
1997
Pages
129 - 133
Database
ISI
SICI code
0001-2815(1997)49:2<129:DOPFTI>2.0.ZU;2-1
Abstract
A PCR-SSOP typing method, involving a single PCR amplification in conj unction with 19 digoxigenin labelled oligonucleotide probes, has been developed for the identification of 17 known HLA-A02 alleles. The met hod has been applied to four populations (Northern Ireland, Singapore Chinese, Shetland Island and Mexican) and percentages of HLA-A02 alle les determined within each population.