FULL-TERM PREGNANCY WITH EMBRYOS FROM DONATED OOCYTES IN A 36-YEAR-OLD WOMAN ALLOGRAFTED FOR CHRONIC MYELOID-LEUKEMIA

Authors
RIO B LETURKONIRSCH H AJCHENBAUMCYMBALISTA F BAUDUER F DEZIEGLER D PELISSIER C BERNADOU A FRYDMAN R ZITTOUN R
Citation
B. Rio et al., FULL-TERM PREGNANCY WITH EMBRYOS FROM DONATED OOCYTES IN A 36-YEAR-OLD WOMAN ALLOGRAFTED FOR CHRONIC MYELOID-LEUKEMIA, Bone marrow transplantation, 13(4), 1994, pp. 487-488
Citations number
10
Categorie Soggetti
Hematology,Oncology,Immunology
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
13
Issue
4
Year of publication
1994
Pages
487 - 488
Database
ISI
SICI code
0268-3369(1994)13:4<487:FPWEFD>2.0.ZU;2-B
Abstract
We report the first case of full-term pregnancy arising from donated o ocytes in a 36-year-old woman with chronic myeloid leukemia (CML), 6 y ears after allogeneic bone marrow transplantation (BMT) following tota l body irradiation (TBI) (12 Gy) and cyclophosphamide 120 mg/kg. The f irst attempt at implantation with her own cryopreserved ovocytes was u nsuccessful. Thereafter, she became pregnant after donated oocyte impl antation using estradiol and progesterone support replacing the defect ive ovarian function. The baby was normal. Unfortunately, 6 months lat er, she relapsed in chronic phase of CML.