Citation
Rl. Tolman et Ga. Doss, STRUCTURE DETERMINATION OF 4-CHLORO-DRB, Nucleosides & nucleotides, 13(1-3), 1994, pp. 293-295
Citations number
16
Categorie Soggetti
Biology
Journal title
ISSN journal
07328311
Volume
13
Issue
1-3
Year of publication
1994
Pages
293 - 295
Database
ISI
SICI code
0732-8311(1994)13:1-3<293:SDO4>2.0.ZU;2-Z
Abstract
'Chloro-DRB' beta-D-ribofuranosyl-4,5,6-trichlorobenzimidazole) was pr
epared in the 1950's and shown to be more potent than DRB as an inhibi
tor of RNA synthesis. The ambiguous location of the third chlorine ato
m has been determined by nOe studies to be at the 4-position.