A RIBONOLACTONE-BASED APPROACH TO THE SYNTHESIS OF 1'-CARBON-SUBSTITUTED THYMINE RIBONUCLEOSIDES

Authors
HAYAKAWA H MIYAZAWA M TANAKA H MIYASAKA T
Citation
H. Hayakawa et al., A RIBONOLACTONE-BASED APPROACH TO THE SYNTHESIS OF 1'-CARBON-SUBSTITUTED THYMINE RIBONUCLEOSIDES, Nucleosides & nucleotides, 13(1-3), 1994, pp. 297-308
Citations number
20
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
13
Issue
1-3
Year of publication
1994
Pages
297 - 308
Database
ISI
SICI code
0732-8311(1994)13:1-3<297:ARATTS>2.0.ZU;2-I
Abstract
Thymine ribonucleosides bearing a carbon substituent at the anomeric p osition were synthesized starting from D-ribonolactone by way of nucle ophilic addition reaction of organolithium reagents and subsequent con densation with trimethylsilylated thymine.