SYNTHESIS OF THE NUCLEOTIDE ANALOG - (R,S)-9-[1-(2-HYDROXYETHYLTHIO)-2-PHOSPHONYLETHYL] ADENINE

Authors
LAZREK HB KHAIDER H ROCHDI A BARASCUT JL IMBACH JL
Citation
Hb. Lazrek et al., SYNTHESIS OF THE NUCLEOTIDE ANALOG - (R,S)-9-[1-(2-HYDROXYETHYLTHIO)-2-PHOSPHONYLETHYL] ADENINE, Nucleosides & nucleotides, 13(1-3), 1994, pp. 811-817
Citations number
13
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
13
Issue
1-3
Year of publication
1994
Pages
811 - 817
Database
ISI
SICI code
0732-8311(1994)13:1-3<811:SOTNA->2.0.ZU;2-R
Abstract
The acyclic nucleotide analogue (R,S)-9-1-(2-hydroxyethylthio)-2-phos phonylethyl adenine HETPEA, 4 was prepared by coupling the adenine potassium salt with diethyl ethynylphosphonate followed by condensatio n of the product with 2-mercaptoethanol.