INTERPENETRATING HYDROGEL NETWORKS BASED ON GELATIN AND POLYACRYLAMIDE - SYNTHESIS, SWELLING, AND DRUG-RELEASE ANALYSIS

Authors
RAMARAJ B RADHAKRISHNAN G
Citation
B. Ramaraj et G. Radhakrishnan, INTERPENETRATING HYDROGEL NETWORKS BASED ON GELATIN AND POLYACRYLAMIDE - SYNTHESIS, SWELLING, AND DRUG-RELEASE ANALYSIS, Journal of applied polymer science, 52(7), 1994, pp. 837-846
Citations number
30
Categorie Soggetti
Polymer Sciences
Journal title
Journal of applied polymer science → ACNP
ISSN journal
00218995
Volume
52
Issue
7
Year of publication
1994
Pages
837 - 846
Database
ISI
SICI code
0021-8995(1994)52:7<837:IHNBOG>2.0.ZU;2-Y
Abstract
Interpenetrating hydrogel network has been synthesized from gelatin an d polyacrylamide by cross-linking with their respective cross-linking agents. The swelling behavior of this Interpenetrating polymer network (IPN) system was analyzed in water and in citric acid-phosphate buffe r solution at various pH. The effect of temperature on swelling behavi or of these gels has been analyzed by. variation from 25 to 60-degrees -C at physiological pH. The drug release behavior of these gels was al so analyzed with temperature variation at physiological pH. (C) 1994 J ohn Wiley & Sons, Inc.