SEPARATION OF HEMOGLOBIN-F, HEMOGLOBIN-FA C, HEMOGLOBIN-S, HEMOGLOBIN-C, HEMOGLOBIN-A1C AND TITRATION OF HEMOGLOBIN-F USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Authors
PIC P DUCROCQ R GIROT R
Citation
P. Pic et al., SEPARATION OF HEMOGLOBIN-F, HEMOGLOBIN-FA C, HEMOGLOBIN-S, HEMOGLOBIN-C, HEMOGLOBIN-A1C AND TITRATION OF HEMOGLOBIN-F USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Annales de biologie clinique, 52(2), 1994, pp. 129-132
Citations number
9
Categorie Soggetti
Medicine, Research & Experimental",Biology
Journal title
Annales de biologie clinique → ACNP
ISSN journal
00033898
Volume
52
Issue
2
Year of publication
1994
Pages
129 - 132
Database
ISI
SICI code
0003-3898(1994)52:2<129:SOHHCH>2.0.ZU;2-M
Abstract
Separation of hemoglobins F, Fac, S, C and Ale was performed using hig h performance liquid chromatography with a cation exchange Polycat A c olumn in a 15-minute assay. HbF titration results were well correlated with those of the reference alkali denaturation technique for values below 12% (r = 0,95; P < 0.001). This technique may be used as a confi rmation test for neonatal screening of sickle cell disease.