Cancer pain treatment is well established. The World Health Organizati
on provides clinicians an ''analgesic ladder'' scheme to optimize canc
er pain treatment. At the beginning of the pain treatment, oral analge
sic administration is preferred. The analgesic dose must be individual
ized. Many published papers describe the spinal administration of opio
ids in combination with various other drugs such as bupivacaine in sel
ected patients with cancer pain. Although complications have been repo
rted to be few, some recent reports debate this idea. We first describ
e a population of 92 cancer patients, 13 of whom received intrathecal
morphine. We then present our experience with a separate group of 33 c
ancer patients who were also managed using intrathecal morphine. Based
on this experience, the generally accepted indications for the techni
que appeared to be justified. Concern about spinal infection is well c
onsidered, however. Three out of those patients developed meningitis,
a complication rate that is far too high.