GENEALOGY AND CLINICAL-APPEARANCE OF FAMI LY HYPERLIPIDEMIA TYPE-IIA AND TYPE-IIB

To analyze genealogical and clinical characteristics of family hyperli pidemia type IIa and IIb, the author examined 40 probands an 179 close relatives. Blood lipid composition was investigated in 85 of them. Hy perlipidemia was found in 42 examinees which is in accordance with pre vious findings on this trait inheritance. Sons inherit hyperlipidemia from their fathers more frequently than daughters (60.0 % against 40.0 %, respectively). Coronary heart disease and other related clinical c onditions arose more frequently in probands than in their relatives wi th hyperlipidemia though 10-year mortality in them was actually the sa me: 20.0 and 18,6%, respectively.