Authors
Citation
T. Elbert et al., SYNTHESIS OF THE C-14-LABELED JUVENOID W328, Journal of labelled compounds & radiopharmaceuticals, 34(4), 1994, pp. 377-382
Citations number
6
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy
Journal title
ISSN journal
03624803
Volume
34
Issue
4
Year of publication
1994
Pages
377 - 382
Database
ISI
SICI code
0362-4803(1994)34:4<377:SOTCJW>2.0.ZU;2-E
Abstract
The labelled juvenoid 2-(4-(2-(ethoxycarbamatoethoxy) (benzene-U-C-14)
benzyl)-1-cyclohexanone ethylene acetal (8) (W 328) was prepared star
ting from p-hydroxy(ring-U-C-14) benzoic acid (1) by a seven step synt
hesis in 11% overall yield. The reaction conditions previously reporte
d for the ''cold'' synthesis of the W 328 (B) were modified to suit th
e small scale preparation.