ASYMMETRIC-SYNTHESIS .30. SYNTHESIS OF 3-SUBSTITUTED PIPERIDINES FROMCHIRAL NON-RACEMIC LACTAMS

Authors
MICOUIN L VAREA T RICHE C CHIARONI A QUIRION JC HUSSON HP
Citation
L. Micouin et al., ASYMMETRIC-SYNTHESIS .30. SYNTHESIS OF 3-SUBSTITUTED PIPERIDINES FROMCHIRAL NON-RACEMIC LACTAMS, Tetrahedron letters, 35(16), 1994, pp. 2529-2532
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
16
Year of publication
1994
Pages
2529 - 2532
Database
ISI
SICI code
0040-4039(1994)35:16<2529:A.SO3P>2.0.ZU;2-W
Abstract
A series of 3-substituted piperidines in enantiomerically pure form ha s been synthetized from lactam 3 by a stereospecific route involving a postulated rigid amide enolate. This strategy has been applied to the synthesis of (+)-stenusine 10.