ASYMMETRIC-SYNTHESIS .31. SYNTHESIS OF 2-SUBSTITUTED PIPERAZINES FROMCHIRAL NON-RACEMIC LACTAMS

Authors
SCHANEN V RICHE C CHIARONI A QUIRION JC HUSSON HP
Citation
V. Schanen et al., ASYMMETRIC-SYNTHESIS .31. SYNTHESIS OF 2-SUBSTITUTED PIPERAZINES FROMCHIRAL NON-RACEMIC LACTAMS, Tetrahedron letters, 35(16), 1994, pp. 2533-2536
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
16
Year of publication
1994
Pages
2533 - 2536
Database
ISI
SICI code
0040-4039(1994)35:16<2533:A.SO2P>2.0.ZU;2-#
Abstract
The preparation of lactam 2 from R-(-)-phenylglycinol and N-Boc glycin e is described. Diastereoselective alkylation of 2 allowed the prepara tion of piperazine derivatives in an optically pure form.