BINDING OF HEAT-SHOCK PROTEIN-70 (HSP70) TO TUBULIN

Authors
SANCHEZ C PADILLA R PACIUCCI R ZABALA JC AVILA J
Citation
C. Sanchez et al., BINDING OF HEAT-SHOCK PROTEIN-70 (HSP70) TO TUBULIN, Archives of biochemistry and biophysics, 310(2), 1994, pp. 428-432
Citations number
35
Categorie Soggetti
Biology,Biophysics
Journal title
Archives of biochemistry and biophysics → ACNP
ISSN journal
00039861
Volume
310
Issue
2
Year of publication
1994
Pages
428 - 432
Database
ISI
SICI code
0003-9861(1994)310:2<428:BOHP(T>2.0.ZU;2-P
Abstract
Binding of heat-shock protein (hsp70) to polymerized tubulin has been investigated by in vitro experiments. The tubulin region involved in b inding to hsp70 corresponds to the carboxy-terminal residues 431-444, also involved in the association with other microtubule-associated pro teins (MAPs). Additionally, the putative tubulin binding motif in the hsp70 protein contains a sequence related to the motif described for M AP1B protein. (C) 1994 Academic Press, Inc.