Binding of heat-shock protein (hsp70) to polymerized tubulin has been
investigated by in vitro experiments. The tubulin region involved in b
inding to hsp70 corresponds to the carboxy-terminal residues 431-444,
also involved in the association with other microtubule-associated pro
teins (MAPs). Additionally, the putative tubulin binding motif in the
hsp70 protein contains a sequence related to the motif described for M
AP1B protein. (C) 1994 Academic Press, Inc.