T. Kanmoto et al., STEROIDAL CONSTITUENTS FROM THE UNDERGROUND PARTS OF REINECKEA-CARNEAAND THEIR INHIBITORY ACTIVITY ON CAMP-PHOSPHODIESTERASE, Chemical and Pharmaceutical Bulletin, 42(4), 1994, pp. 926-931
Phytochemical analysis of the underground parts of Reineckea carnea re
sulted in the finding of twelve steroidal constituents, five of which
appeared to be new compounds and one to be the first isolation from a
natural source. The identification and structural determination of the
steroidal compounds were established by spectroscopic analysis and hy
drolysis. The isolated saponins were evaluated for inhibitory activity
on cAMP phosphodiesterase as a primary screening test to find new med
icinal materials.