The lack of an accepted method of accurate and objective measurement o
f wound dimensions is a major obstacle to the assessment of effective
wound management regimes. This study compares three different wound vo
lume measurement techniques (filling the lesion with saline, molding o
f a dental impression material and a computer vision method based on i
mage processing and the Structured Light technique) in terms of accura
cy, precision and practicability in a clinical environment. Three grou
ps of hospital staff, doctors, nurses and technicians, repeatedly meas
ured a set of 6 different models of wounds. Measuring wound volume by
filling it with saline produces results with standard deviations betwe
en 9% and 18% of the actual volume. Dental impression material perform
s better, between 5% and 16%, but is difficult to apply and time consu
ming to use. Apart from the advantage of providing instant optical rec
ords of wounds, the image processing method produces more reliable vol
ume measurements with a standard deviation of between 3% and 15%. The
results demonstrate that the computer based method yields the most rep
roducible results with a minimum of inter-observer error but the metho
d is not applicable for undermined, very deep and very large wounds.