LON PROTEASE IS INVOLVED IN TRANSCRIPTION REGULATION OF LUX OPERON OFVIBRIO-FISCHERI

Authors
ZAVILGELSKII GB MANUKHOV IV
Citation
Gb. Zavilgelskii et Iv. Manukhov, LON PROTEASE IS INVOLVED IN TRANSCRIPTION REGULATION OF LUX OPERON OFVIBRIO-FISCHERI, Genetika, 30(3), 1994, pp. 337-341
Citations number
10
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
30
Issue
3
Year of publication
1994
Pages
337 - 341
Database
ISI
SICI code
0016-6758(1994)30:3<337:LPIIIT>2.0.ZU;2-F
Abstract
Lon protease of Escherichia coli specifically inhibits the activity of the regulatory protein LuxI responsible for synthesis of the autoindu cer N-(3-oxo-hexanoyl)homosetine lactone. As a result, transcription o f the right lux operon is initiated in lon(+) bacteria much later than in lon(-) mutants. Loa protease does not affect the activity of LuxAB proteins (luciferase)and LuxC, LuxD, and LuxE proteins involved in sy nthesis of an aldehyde substrate for luciferase.