THE HUMAN HOMOLOG OF THE RETROVIRAL ONCOGENE QIN MAPS TO CHROMOSOME 14Q13

Authors
KASTURY K LI J DRUCK T SU HY VOGT PK CROCE CM HUEBNER K
Citation
K. Kastury et al., THE HUMAN HOMOLOG OF THE RETROVIRAL ONCOGENE QIN MAPS TO CHROMOSOME 14Q13, Proceedings of the National Academy of Sciences of the United Statesof America, 91(9), 1994, pp. 3616-3618
Citations number
20
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Proceedings of the National Academy of Sciences of the United Statesof America → ACNP
ISSN journal
00278424
Volume
91
Issue
9
Year of publication
1994
Pages
3616 - 3618
Database
ISI
SICI code
0027-8424(1994)91:9<3616:THHOTR>2.0.ZU;2-1
Abstract
Chromosomal mapping of the human QIN gene (renamed FKH2 by the Human G enome Organization Nomenclature Committee) was initially accomplished by correlation of the presence of the QIN locus with specific chromoso me regions in a rodent-human hybrid panel. This analysis revealed that the human QIN gene maps to chromosome region 14q11.2 --> 14q32, betwe en the TCR and IGH loci. Further analysis by fluorescence in situ hybr idization techniques with a human QIN genomic clone refined the human QIN gene localization to 14q13.