Reports have focused on the perceived benefit of a new method of manag
ing pancreatic necrosis and sepsis: leaving the abdomen packed open af
ter debridement, the ''marsupialization'' technique. We have continued
to treat infected pancreatic necrosis with aggressive pancreatic debr
idement and drainage, closure of the abdomen, and prompt reoperation a
s often as necessary if further sepsis is identified. We report 52 con
secutive patients with infected pancreatic necrosis operated upon betw
een July, 1972 and March, 1990. Postoperative organ failure and APACHE
II scoring correlated with survival. Patients with APACHE II scores l
ess than 15 had an operative mortality rate of 4 per cent, whereas pat
ients with scores greater than 15 had a 44 per cent mortality rate. We
recognize that no two retrospective series are truly comparable, but
in comparison to published reports on the open technique, fascial clos
ure after pancreatic debridement appeared to produce fewer wound compl
ications (only one dehiscence and one incisional hernia) and fewer tri
ps to the operating room.