UNUSUAL REACTIVITY OF 4-CARBOXYAMIDO-2-OXAZOLINE SYSTEMS - NEW SYNTHESIS OF OPTICALLY-ACTIVE N-SULFONYL DERIVATIVES

Authors
COSSU S GIACOMELLI G CONTI S FALORNI M
Citation
S. Cossu et al., UNUSUAL REACTIVITY OF 4-CARBOXYAMIDO-2-OXAZOLINE SYSTEMS - NEW SYNTHESIS OF OPTICALLY-ACTIVE N-SULFONYL DERIVATIVES, Tetrahedron, 50(17), 1994, pp. 5083-5090
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
17
Year of publication
1994
Pages
5083 - 5090
Database
ISI
SICI code
0040-4020(1994)50:17<5083:URO4S->2.0.ZU;2-0
Abstract
Optically active 2-alkyl-2-oxazoline-4-carboxyamides, derived from ena ntiomeric pure alpha-amino-beta-hydroxy acids, react with aryl- and al kyl sulphonyl chlorides in pyridine affording the corresponding optica lly active 2-alkyl-2-oxazoline-4-carboxyamido-N-sulphonyl derivatives without appreciable racemization.