Gl. Daikos et al., HEPATITIS-C VIRUS-INFECTION IN A SEXUALLY ACTIVE INNER-CITY POPULATION - THE POTENTIAL FOR HETEROSEXUAL TRANSMISSION, Infection, 22(2), 1994, pp. 72-76
The prevalence of hepatitis C virus (HCV) infection and associated ris
k factors in an inner city sexually active heterosexual population par
ticipating in a prospective study for the evaluation of heterosexual t
ransmission of human immunodeficiency virus type-1 (HIV-1) were examin
ed. Individuals,vith prior history of injection drug use or receipt of
blood products were excluded from the study. Of 571 participants, 25
(4.4%) were seropositive for HCV, 39 (7%) for HIV, and 125 (22%) for h
epatitis B virus (HBV). Multivariate analysis revealed that those with
more than ten heterosexual partners in the past 5 years (OR = 3.7; 95
% CI = 1.3, 10.2; P = 0.01), engaging in sexual practices more than on
ce per week (OR = 3.3; 95% CI = 1.1, 10.1; P = 0.04), with antibody to
hepatitis B core (HBc) antigen(OR = 2.9; 95% CI = 1.1, 7.4; P = 0.03)
, and antibody to HIV-1 (OR = 5.8; 95% CI = 1.9; 17.6; P = 0.002) were
independently associated with HCV infection. These findings suggest t
hat heterosexual transmission of HCV may occur in an inner city sexual
ly active heterosexual population.