Pneumopericardium, the presence of air in the pericardial space, is a
rare disorder that is usually caused by trauma. We describe a patient
given induction chemotherapy for acute myelogenous leukemia who develo
ped pulmonary aspergillosis that resulted in pericarditis and pneumope
ricardium. He responded to antifungal treatment and recovered from gra
nulocytopenia, but died early during the next course of chemotherapy.
Two other reported cases of pneumopericardium associated with pulmonar
y aspergillosis are summarized.