XANTHOMA DISSEMINATUM ASSOCIATED WITH HYPOCHOLESTEROLEMIA AND HYPOLIPOPROTEINEMIA

Xanthoma disseminatum is a rare form of non-X Histiocytosis, of which fewer than 100 cases have been reported. It is considered a normolipid emic xanthomatosis because of the absence of hyperlipidemia and lipopr otein abnormalities in these patients. A 50-year-old man presented a 1 4-year history of multiple papules and nodules, yellow-brown colored, mainly located on his face, neck and upper trunk. Histological and imm unocytochemical findings confirmed the diagnosis of Xanthoma dissemina tum. A lipidic examination revealed hypocholesterolemia and hypolipopr oteinemia affecting both low density lipoprotein (LDL) and high densit y lipoprotein (HDL).