VONRECKLINGHAUSENS-DISEASE WITH LUNG-CANCER DERIVED FROM THE WALL OF EMPHYSEMATOUS BULLAE

A 53-year-old male with von Recklinghausen's disease, diagnosed to hav e metastatic large cell carcinoma in the left supraclavicular lymph no de, was admitted for radiotherapy. No other primary lesions were found . Emphysematous bullae in both upper lung fields were seen on chest ro entgenograph, and the leucocyte count and G-CSF level were extremely e levated. Later, when metastases appeared, systemic chemotherapy was su pplemented, but in vain. An autopsy showed large cell carcinoma of the lung derived from the wall of emphysematous bullae in left lung along with multiple metastases. The presence of von Recklinghausen's diseas e, emphysematous bullae and lung cancer together are noteworthy.