O. Gunhan et al., A COMPARATIVE HISTOLOGICAL STUDY OF NONPOROUS AND MICRO-POROUS (ALGAE-DERIVED) HYDROXYLAPATITE CERAMICS, Australian dental journal, 39(1), 1994, pp. 25-27
Two different types of hydroxylapatite ceramics were examined histolog
ically to assess their effects on the healing of standardized bone def
ects drilled in the mandibular bone of beagles. After 40 days both mat
erials were totally enclosed by newly-formed bone, but only the defect
s filled with micro-porous hydroxylapatite were found to show bone inc
orporation which is a good indicator of implant stability. These resul
ts suggest that the physio-chemical similarities between the micro-por
ous hydroxylapatite and native bone may promote effective bone incorpo
ration which can increase the stability of implants.