AN APPROACH TOWARDS THIOL MEDIATED LABELING IN THE MINOR-GROOVE OF OLIGONUCLEOTIDES

Authors
DOUGLAS ME BEIJER B SPROAT BS
Citation
Me. Douglas et al., AN APPROACH TOWARDS THIOL MEDIATED LABELING IN THE MINOR-GROOVE OF OLIGONUCLEOTIDES, Bioorganic & medicinal chemistry letters, 4(8), 1994, pp. 995-1000
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
8
Year of publication
1994
Pages
995 - 1000
Database
ISI
SICI code
0960-894X(1994)4:8<995:AATTML>2.0.ZU;2-9
Abstract
The preparation of an appropriately protected 2'-O-(2-thioethyl)uridin e phosphoramidite is reported along with its incorporation into an oli gonucleotide and post-synthetic labelling.