SYNTHESIS AND PHYSICAL-PROPERTIES OF SULFONAMIDE-CONTAINING OLIGONUCLEOTIDES

Authors
MCELROY EB BANDARU R HUANG JX WIDLANSKI TS
Citation
Eb. Mcelroy et al., SYNTHESIS AND PHYSICAL-PROPERTIES OF SULFONAMIDE-CONTAINING OLIGONUCLEOTIDES, Bioorganic & medicinal chemistry letters, 4(8), 1994, pp. 1071-1076
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
8
Year of publication
1994
Pages
1071 - 1076
Database
ISI
SICI code
0960-894X(1994)4:8<1071:SAPOSO>2.0.ZU;2-T
Abstract
Sulfonamide-linked thymidine dimers have been prepared and incorporate d into oligodeoxynucleotides. Oligos containing up to four sulfonamide linkages have been tested for their ability to form duplexes with com plementary DNA.