LACTATE TRANSPORT ACROSS THE BOVINE RUMEN EPITHELIUM IN-VITRO

The in vitro transport of L-lactate across rumen epithelium was found to be a passive, mass-action regulated diffusion, and no saturable tra nsport mechanisms were involved at concentrations from 2-20 mmol/L. Du ring this increase in L-lactate concentrations the epithelial resistan ce and potential difference increased significantly, indicating an epi thelial change cowards more tight epithelium. The net sodium transport was significantly reduced by 45 % at 20 mmol/L lactate as compared to lactate free conditions.