We tested the colour vision of 72 people with Down's syndrome using th
e Ishihara test and an anomaloscope. We found that 13 of the subjects,
6 males and 7 females, had defective colour vision according to Pickf
ord's classification. In monocular vision 10 eyes were protan (five si
mple, three extreme and two deviant), one eye was simple deuteranomalo
us and the remaining eyes were normal: in binocular vision four of the
subjects were protan (two simple and two deviant), two subjects were
deutan (one simple and one deviant) and the rest were normal. Many of
our subjects had lens opacities, strabismus, nystagmus, hypermetropia,
high myopia and astigmatism, confirming literature reports. The contr
ast sensitivity function measured with the VCTS test showed a consider
able loss of low-frequency sensitivity in our subjects compared to a n
ormal population, which was more marked in the more severely impaired
subjects.