Background: The basic issue of primary prevention strategies of corona
ry heart disease is an individually adapted cardiovascular risk factor
management. However, transformation of these strategies by health car
e professionals is still insufficient, as was demonstrated by three st
udies performed in private practice. Methods and results: In oral gluc
ose tolerance tests performed in 234 patients with essential hypertens
ion who were under regular medical control, 25,6% turned out to have p
reviously unknown diabetes and 41,4% had impaired glucose tolerance. I
n the remaining 33,3% with normal glucose tolerance, mean total serum
cholesterol was 260 mg/dl. 82 patients with essential hypertension and
known diabetes had a mean total serum cholesterol of 276 mg/dl. Neith
er cohort was under lipid lowering drugs. Out of 290 unselected patien
ts treated for type 11-diabetes in private practice, 62% were hyperten
sive. Of those, hypertension was not known untreated or not sufficient
ly treated in 78,2%. Conclusion: As a consequence, in patients at high
cardiovascular risk, not only the ''leading'' disease (i.e. diabetes,
hypertension, hyperlipidaemia), but also the concomitant constellatio
n deserves attention and early intervention.