C. Defelice et al., CHANGES IN CEREBROSPINAL-FLUID BIOTINIDASE ACTIVITY IN STAPHYLOCOCCUS-AUREUS MENINGITIS, Brain & development, 16(2), 1994, pp. 156-158
An early increase in activity of biotinidase in the cerebrospinal flui
d (CSF) during the course of acute Staphylococcus aureus meningitis in
a subject with subacute sclerosing panencephalitis (SSPE) is reported
. A possible role of CSF biotinidase in the hydrolysis of specific opi
oid neuropeptides during acute inflammatory processes involving the CS
F-central nervous system compartment is suggested.