LONG-TIME RESULTS OF SURGICAL THERAPY FOR COLORECTAL-CANCER - RESULTSOF THE GERMAN-STUDY-GROUP-FOR-COLORECTAL-CANCER (SGCRC)

Authors
HERMANEK P WIEBELT H RIEDL S STAIMMER D HERMANEK P BARTELMANN U GALL FP MEWES R GIEDL J FARTHMANN E HARING R KIRCHNER R HELLERICH U SCHAEFER HE WITTEKIND C DORNER A PETERSEN P SCHREIBER HW LONING T AMBERGER H FRIEDL P HERFARTH C WAGNER G WAHRENDORF J WIEBELT H MOLLER P OTTO HF BAUER G HESTERBERG R HILLER C RICHTER E ROTHMUND M STAHLKNECHT CD SCHMITZMOORMANN P SINN HP BERGMANN U HINDRINGER B STAIMMER D WILHELM A SEIB HJ VOETH C WURSTER K HUBER F KLEIN F MENZEL C MORK HH SCHMIDT DS
Citation
P. Hermanek et al., LONG-TIME RESULTS OF SURGICAL THERAPY FOR COLORECTAL-CANCER - RESULTSOF THE GERMAN-STUDY-GROUP-FOR-COLORECTAL-CANCER (SGCRC), Chirurg, 65(4), 1994, pp. 287-297
Citations number
46
Categorie Soggetti
Surgery
Journal title
Chirurg → ACNP
ISSN journal
00094722
Volume
65
Issue
4
Year of publication
1994
Pages
287 - 297
Database
ISI
SICI code
0009-4722(1994)65:4<287:LROSTF>2.0.ZU;2-P
Abstract
In a prospective multicentre observation study with free choice of tre atment 1157 patients with solitary colonic carcinoma were entered free of selection between August 1984 and November 1986. The 5-year-surviv al rate for all patients was observed 45.7 +/- 3.0%, relative (age-cor rected) 60.2 +/- 4.0%. Multivariate analysis using multiple logistic r egression analysis identified R-classification, stage, institution and timing of surgery as independent prognostic factors regarding surviva l. In R0 resected patients occurrence of locoregional recurrence was t he strongest prognostic factor. Study data could demonstrate a substan tial variability in frequency of locoregional recurrence and survival among the participating institutions. The data support the importance of application of principles of radical surgery and gives evidence for the outstanding importance of surgery for the prognosis of colonic ca rcinoma.