Laparoscopic cholecystectomy requires new and specially designed instr
uments. Both, disposable and reusable instruments are available and fr
equently used. The purpose of this analysis was to compare these instr
uments with regard to safety and costs. A complete and detailed calcul
ation comprising all cost components was performed using data from 534
patients. Safety of the procedure was assessed by the documentation o
f all events during and after laparoscopic cholecystectomy in 1000 con
secutive patients. Costs: A standard operation with reusable instrumen
ts costs DM 3395. One third of these costs are non-hospital costs. Eve
ry postoperative day in hospital adds DM 234.44, every minute of opera
tion time adds DM 4.88. Using a complete set of disposable instruments
causes an increase in total costs of DM 1117, which mainly results fr
om the costs of the instruments themselves. Safety: Among 1000 operati
ons all performed with reusable instruments, 82.3% were uneventful for
the patient. The wound infection rate was 2.3%. Until today no injuri
es of the staff caused by these instruments were observed. These findi
ngs demonstrate that reusable instruments are safe and cost-effective.