Hw. Wang et al., NORADRENERGIC INNERVATION OF JUVENILE NASOPHARYNGEAL ANGIOFIBROMA, European archives of oto-rhino-laryngology, 251(2), 1994, pp. 123-126
The glyoxylic catecholaminergic histofluorescence method was employed
on tissues from five cases of juvenile nasopharyngeal angiofibroma in
order to study the sympathetic innervation present. There was no sympa
thetic innervation identified in tumor parenchyma while some scant nor
adrenergic fibers were found in the tumor border. These findings indic
ate that keeping a dissection surface out of tumor during planned exci
sions may be very important, as vessels there have more sympathetic in
nervation which will then result in good vessel contraction in control
ling bleeding. Non-diseased nasal mucosa from each patient was used as
control tissue, with its submucosa seen to be filled with noradrenerg
ic innervation. Some noradrenergic fibers were also found to innervate
the muscle layers of arterioles or venules adjacent to the sphenopala
tine foramen.