EVALUATION OF MRI-MEG EEG CO-REGISTRATION STRATEGIES USING MONTE-CARLO SIMULATION/

We present a Monte Carlo analysis method for evaluating MRI-MEG/EEG co registration techniques. The method estimates the error in co-registr ation as a function of position within the brain. Using this analysis technique, we demonstrate the limitations of conventional head-based f iducial point methods, and propose a new strategy utilising a dental b ite-bar incorporating accurately machined fiducial markers. Results pr esented demonstrate the improved accuracy of MEG/EEG to MRI co-registr ation using the bite-bar. (C) 1997 Elsevier Science Ireland Ltd.