BIOTRANSFORMATION OF SESQUITERPENES BY CULTURED-CELLS .2. BIOTRANSFORMATION OF GERMACRONE BY SUSPENSION-CULTURED CELLS

Authors
SAKAMOTO S TSUCHIYA N KUROYANAGI M UENO A
Citation
S. Sakamoto et al., BIOTRANSFORMATION OF SESQUITERPENES BY CULTURED-CELLS .2. BIOTRANSFORMATION OF GERMACRONE BY SUSPENSION-CULTURED CELLS, Phytochemistry, 35(5), 1994, pp. 1215-1219
Citations number
17
Categorie Soggetti
Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
35
Issue
5
Year of publication
1994
Pages
1215 - 1219
Database
ISI
SICI code
0031-9422(1994)35:5<1215:BOSBC.>2.0.ZU;2-4
Abstract
The transformation of germacrone, a 10-membered ring sesquiterpene, by suspension cultured cells of Lonicera japonica, Bupleurum falcatum, P olygonum tinctorium and Solidago altissima, was investigated. Germacro ne was converted into several types of sesquiterpenes, such as guaiane , eudesmane and seco-guaiane and their structures were determined from spectral and chemical evidence. The configurations of some of the pro ducts were determined by CD spectroscopy. The differences of the kinds of products among the four suspension cultured cells is discussed.