Two new neo-clerodane derivatives, scutalpin E and scutalpin F, have b
een isolated from the acetone extract of the aerial parts of Scutellar
ia alpina. The structures of scutalpin E (7 beta,19-diacetoxy-6 alpha-
tigloyloxy-4 alpha, 18:8 beta 13R-diepoxy-neo-clerodan-15, 16-olide) a
nd scutalpin F (6 alpha, 7 beta, 19-triacetoxy-4 alpha, 18:8 beta, 13S
-diepoxy-neo-clerodan-15, 16-olide) were established mainly by spectro
scopic methods.