USE OF CA-19-9 IN THE EARLY DETECTION OF RECURRENCES IN COLORECTAL-CANCER - COMPARISON WITH CEA

Authors
FILELLA X MOLINA R PIQUE JM GARCIAVALDECASAS JC GRAU JJ NOVELL F ASTUDILLO E DELACY A DANIELS M BALLESTA AM
Citation
X. Filella et al., USE OF CA-19-9 IN THE EARLY DETECTION OF RECURRENCES IN COLORECTAL-CANCER - COMPARISON WITH CEA, Tumor biology, 15(1), 1994, pp. 1-6
Citations number
22
Categorie Soggetti
Oncology
Journal title
Tumor biology → ACNP
ISSN journal
10104283
Volume
15
Issue
1
Year of publication
1994
Pages
1 - 6
Database
ISI
SICI code
1010-4283(1994)15:1<1:UOCITE>2.0.ZU;2-K
Abstract
The serum levels of CA 19-9 were determined in the follow-up of 370 pa tients with colorectal cancer and compared with CEA. An increase in CA 19-9 preceded clinical diagnosis of recurrence in 25% of 72 patients. The mean time between the rise in CA 19-9 and clinical diagnosis of r elapse was 3.7 months (median 3). Sensitivity of CA 19-9 in the early diagnosis of recurrence was much lower than that obtained for CEA (75% ). Only 1 patient had elevated CA 19-9 levels and normal CEA.