ULTRAVIST - A DRUG OF CHOICE FOR CHILDREN WITH RENAL DYSFUNCTION DURING RADIOPAQUE STUDIES

The nonionic radioopaque ultravist and the high-molar radioopaque vero graffin were studied for their effects on the blood osmotic status of children with lower renal concentrating function. A total of 36 childr en aged 8 months to 12 years who had pyelonephritis, hydronephrosis an d renal injury at their acute stage were studied angiographically unde r general anesthesia. The radioopaque was injected in a mean dose of 2 ml/kg for 2-3 sec. Ultravist was found to have a less osmotic action on the blood osmotic status than did verograffin. The changes in the d etectable major blood osmotic parameters: sodium, potassium, glucose, urea, creatine were less pronounced. Plasma osmolality was moderately increased with ultravist and much higher than its normal values with v erograffin at min 1 after its administration and at hour 2 of the stud y. Ultravist is preferable as a radiopaque used in children with decre ased renal concentrating function.