M. Gundidza et A. Kufa, SKIN IRRITANT AND TUMOR-PROMOTING EXTRACT FROM THE LATEX OF EUPHORBIA-BOUGHEII, Central African Journal of Medicine, 39(3), 1993, pp. 56-60
A crude ethylacetate extract was isolated from Euphorbia bougheii by a
combination of solvent-solvent and chromatographic methods. The extra
ct exhibited significant skin irritant activity on the mouse ear as we
ll as a tumour promoting activity on the mouse back skin. This indicat
es that the use of this plant as a medicine must be discouraged since
the latex extract causes cancer.