CLINICAL-EVALUATION OF DRUG EFFICACY IN UTI IN MEN - THE SIGNIFICANCEOF BACTERIAL ELIMINATION ON DAY ONE

Authors
ARAKAWA S KAMIDONO S
Citation
S. Arakawa et S. Kamidono, CLINICAL-EVALUATION OF DRUG EFFICACY IN UTI IN MEN - THE SIGNIFICANCEOF BACTERIAL ELIMINATION ON DAY ONE, Infection, 22, 1994, pp. 190000023-190000026
Citations number
1
Categorie Soggetti
Infectious Diseases
Journal title
Infection → ACNP
ISSN journal
03008126
Volume
22
Year of publication
1994
Supplement
1
Pages
190000023 - 190000026
Database
ISI
SICI code
0300-8126(1994)22:<190000023:CODEIU>2.0.ZU;2-T
Abstract
With the purpose of assessing whether the effect of a drug at an early stage of administration could serve to predict efficacy at the end of drug treatment, a cephem antibiotic was administered for 5 days (days 0-4) by injection in males with complicated UTI. Results showed that the bacteriological effect on day 1 was reflected in the overall clini cal efficacy on day 5. The activity of an antibacterial agent appeared to be reflected in the ability to eliminate bacteria 1 to 2 days afte r the start of drug administration.