P. Sebert et al., GAMMA-IRRADIATION OF CARBOXYMETHYLCELLULOSE - TECHNOLOGICAL AND PHARMACEUTICAL ASPECTS, International journal of pharmaceutics, 106(2), 1994, pp. 103-108
In this work, we have studied the stability of sodium carboxymethylcel
lulose (NaCMC) powder after irradiation. Its effect on the physical, c
hemical and pharmacotechnical properties has been investigated in orde
r to determine the influence of such treatment on the functional prope
rties of NaCMC, especially on the formulation of gels, suspensions, ta
blets and sustained release parenteral dosage forms.