Pj. Clayton et al., PREMORBID PERSONALITY-TRAITS OF MEN WHO DEVELOP UNIPOLAR OR BIPOLAR DISORDERS, European archives of psychiatry and clinical neuroscience, 243(6), 1994, pp. 340-346
In 1972, all Swiss males in the Canton of Zurich who reported for a co
mpulsory medical examination for selection for military service were g
iven the Freiburg Personality Inventory. This was repeated in half the
sample on three subsequent occasions. From 1983 to 1988, an effort wa
s made to identify all male psychiatric cases. There were 99 unipolars
and 26 bipolars. The unipolars who had their age of onset after the p
ersonality testing displayed elevated scores on a constellation of sym
ptoms labelled autonomic lability which consisted of items that correl
ated highly with neuroticism. The trait endured even when it was retes
ted at age 36 years. The bipolars did not differ from the controls in
any respect on any occasion.