OBJECTIVE. The purpose of our study was to delineate the interconnecti
ons in the temporal fossa that an visible on high-resolution clinical
images. SUBJECTS AND METHODS. Thin-section MR images and CT scans of t
he temporal fossa in two normal volunteers were obtained in coronal an
d axial sections. MR images, CT scans, or both of 20 patients with dem
onstrable spread of disease were reviewed. RESULTS. The imaging studie
s of patients with disease proved more informative than images of the
normal subject or the published anatomic and surgical descriptions of
the temporal fossa, We recognized five discrete radiographically defin
ed regions. the connective tissue layer, compartment of the superficia
l fat pad, compartment of the deep fat pad, compartment of the tempora
l muscle (superior recess of the suprazygomatic masticator), and subpe
riosteal zone. Important, tortuous, and to our knowledge undescribed i
nterconnections between the scalp, posterior neck, eyelid, face, and t
he suprazygomatic masticator were delineated. CONCLUSION. Imaging stud
ies of the temporal fossa can be used to formulate a clinically useful
approach that simplifies the complex anatomy of the temporal fossa.