VIBRIO-CHOLERAE O139 SYNONYM BENGAL IS CLOSELY-RELATED TO VIBRIO-CHOLERAE EL-TOR BUT HAS IMPORTANT DIFFERENCES

Authors
JOHNSON JA SALLES CA PANIGRAHI P ALBERT MJ WRIGHT AC JOHNSON RJ MORRIS JG
Citation
Ja. Johnson et al., VIBRIO-CHOLERAE O139 SYNONYM BENGAL IS CLOSELY-RELATED TO VIBRIO-CHOLERAE EL-TOR BUT HAS IMPORTANT DIFFERENCES, Infection and immunity, 62(5), 1994, pp. 2108-2110
Citations number
13
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
62
Issue
5
Year of publication
1994
Pages
2108 - 2110
Database
ISI
SICI code
0019-9567(1994)62:5<2108:VOSBIC>2.0.ZU;2-U
Abstract
Although Vibrio cholerae O139 synonym Bengal strains, from the current epidemics in India and Bangladesh, are closely related to seventh-pan demic strains, as shown by multilocus enzyme electrophoresis, Bengal s trains are encapsulated and portions of the O1 antigen biosynthetic co mplex genes found in O1 strains are altered or larking. Encapsulated B engal strains showed resistance to killing by normal human serum. The presence of the capsule suggests the potential for bloodstream invasio n in susceptible hosts and has profound implications for vaccine devel opment.